Table 3 Tolerability of subgroups
n | Treatment completion rate (%) | Relative dose intensities(%) | |||||
|---|---|---|---|---|---|---|---|
6 cycle (%) | 8 cycle (%) | mean | median | ||||
S-1 (%) | Oxaliplatin (%) | S-1 (%) | Oxaliplatin (%) | ||||
Age(years) | |||||||
< 55 | 27 | 20(74.07) | 15(55.56) | 68.74(98.20) | 124.11(95.47) | 68.00(97.14) | 127.00(97.69) |
55~ 65 | 23 | 16(69.57) | 9(39.13) | 69.60(99.43) | 123.74(95.18) | 70.00 (100.00) | 125.00 (96.15) |
≥65 | 4 | 3 (75.00) | 2 (50.00) | 69.75 (99.64) | 116.25 (89.42) | 70.00 (100.00) | 116.50 (89.62) |
Gender | |||||||
Male | 37 | 25 (67.57) | 17 (45.95) | 69.38 (99.11) | 122.32 (94.10) | 70.00 (100.00) | 124.00 (95.38) |
Female | 17 | 14 (82.35) | 9 (52.94) | 68.77 (98.24) | 125.65 (96.65) | 68.00(97.14) | 129.00 (99.23) |
PS(ECOG) | |||||||
0 | 14 | 10 (71.43) | 6 (42.86) | 68.64 (98.06) | 125.29 (96.37) | 68.50 (97.86) | 127.50 (98.08) |
1 | 40 | 29 (72.50) | 20 (50.00) | 69.38 (99.11) | 122.70 (94.38) | 70.00 (100.00) | 123.00 (94.62) |
BSA | |||||||
< 1.7 | 26 | 22 (84.62) | 13 (50.00) | 70.85 (101.21) | 123.96 (95.36) | 71.00 (101.43) | 125.00 (96.15) |
≥1.7 | 28 | 17 (60.71) | 13 (46.43) | 67.64 (96.63) | 122.82 (94.48) | 68.00(97.14) | 126.00 (96.92) |
Type of gastrectomy | |||||||
Total | 9 | 7 (77.78) | 4 (44.44) | 70.33 (100.48) | 121.22 (93.25) | 71.00 (101.43) | 119.00 (91.54) |
Partial | 45 | 32 (71.11) | 22 (48.89) | 68.96 (98.51) | 123.80 (95.23) | 68.00(97.14) | 126.00 (96.92) |