Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

Table 1 Correlation analysis of MELK, STRAP expression and clinical features

Characteristics	Patients n = 51	MELK expression			STRAP expression
Characteristics	Patients n = 51	low	high	P value	low	high	P value
Gender				0.972			0.945
Male	33	13	20		15	18
Female	18	7	11		8	10
Age (year)				0.389			0.741
≥ 60	32	14	18		15	17
< 60	19	6	13		8	11
Tumor size				0.431			0.461
≥ 5 cm	16	5	11		6	10
< 5 cm	35	15	20		17	18
Tumor differention				0.544			0.931
Good	0
Moderate	47	19	28		21	26
Poor	4	1	3		2	2
T-stage				0.026			0.013
1–2	10	7	3		8	2
3–4	41	13	28		15	26
N-stage				0.024			0.991
0	31	16	15		14	17
1–2	20	4	16		9	11
M-stage				0.832			0.491
0	44	17	27		19	25
1	7	3	4		4	3

ISSN: 1471-2407