Skip to main content

Table 1 Cell lines by tissue type, BRAF and RAS mutational status

From: Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells

Cell lines Tissue BRAF BRAF activity RAS (N/K) Reference
A375 melanoma V600E high wild type [45]
CRL5885 lung G466 V low wild type [25]
WM3629 melanoma D594G low G12D (N) [27]
WM3670 melanoma G469E low G12D (N) [27]
MDAMB231 breast G464 V intermediate G13D (K) [46]
CRL5922 lung L597 V intermediate Q61K (N) [47]