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Table 1 Cell lines by tissue type, BRAF and RAS mutational status

From: Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells

Cell lines

Tissue

BRAF

BRAF activity

RAS (N/K)

Reference

A375

melanoma

V600E

high

wild type

[45]

CRL5885

lung

G466 V

low

wild type

[25]

WM3629

melanoma

D594G

low

G12D (N)

[27]

WM3670

melanoma

G469E

low

G12D (N)

[27]

MDAMB231

breast

G464 V

intermediate

G13D (K)

[46]

CRL5922

lung

L597 V

intermediate

Q61K (N)

[47]

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BMC Cancer

ISSN: 1471-2407

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