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Table 3 Top three Epithelial and Stromal features for each of the four experiments: Low ODx and Low mBR grade vs. High ODx and High mBR grade (Low-Low vs. High-High), Low ODx vs. High ODx, Low ODx vs. Intermediate and High ODx, and Low and Intermediate ODx vs. High ODx

From: Quantitative nuclear histomorphometry predicts oncotype DX risk categories for early stage ER+ breast cancer

Experiments

Epithelial Features (EP)

Low Low vs. High High

1

EP: CCG: Clustering Coefficient E

2

EP: CCG: standard deviation edge length

3

EP: CCG: Clustering Coefficient D

Low vs. High

1

EP: CCG: standard deviation edge length

2

EP: CCG: mean edge length

3

EP: Arch: Disorder of Nearest Neighbors in a 40 Pixel Radius

Low vs. Intermediate and High

1

EP: Arch: Disorder of Nearest Neighbors in a 40 Pixel Radius

2

EP: Arch: Disorder of Nearest Neighbors in a 50 Pixel Radius

3

EP: Arch: Avg. Nearest Neighbors in a 40 Pixel Radius

Low and Intermediate vs. High

1

EP: CCG: standard deviation edge length

2

EP: CCG: mean edge length

3

EP: Arch: Disorder of Nearest Neighbors in a 40 Pixel Radius

 

Stromal Features (ST)

Low Low vs. High High

1

ST: Shape: Median Area Ratio

2

ST: Shape: Median Invariant Moment 2

3

ST: Shape: Mean Perimeter Ratio

Low vs. High

1

ST: Shape: Mean Perimeter Ratio

2

ST: Shape: Mean Area Ratio

3

ST: Shape: Mean Invariant Moment 2

Low vs. Intermediate and High

1

ST: Shape: Mean Invariant Moment 2

2

ST: Shape: Median Invariant Moment 2

3

ST: Shape: Standard Deviation Invariant Moment 2

Low and Intermediate vs. High

1

ST: Shape: Median Invariant Moment 2

2

ST: Shape: Mean Invariant Moment 2

3

ST: Shape: Standard Deviation Fourier Descriptor 2