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Fig. 6 | BMC Cancer

Fig. 6

From: Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions

Fig. 6

Comparison of genes of interest between NCH644 and NCH421k. a and b Venn diagrams of the NCH644 and NCH421k dataset. There is a limited overlap of 28 upregulated (a) and 8 downregulated (b) genes in both cell lines. c TULP3 is upregulated in both NCH644 and NCH421k after CIN knockdown. P-values are calculated by DESeq2, shown are RPKM means + SD. d ITGA6 is significantly downregulated in NCH421k after CIN knockdown, whereas BMI1 is upregulated in NCH644. P-values are calculated by DESeq2, shown are RPKM means + SD. (e) and (f) CIN is significantly downregulated in the NGS dataset in both NCH644 (e) and NCH421k (f) (one-way ANOVA followed by Dunnett’s multiple comparisons test, p < 0.001 for both shRNAs). Shown are means + SEM

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BMC Cancer

ISSN: 1471-2407

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