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Fig. 5 | BMC Cancer

Fig. 5

From: Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions

Fig. 5

Next-generation sequencing based characterization of NCH644 and NCH421k CIN knockdown cells. a After CIN knockdown there are 409 upregulated and 258 downregulated genes in NCH644 CIN shRNA cells as compared to CTRL cells. b After CIN knockdown there are 172 upregulated and 66 downregulated genes in NCH421k CIN shRNA cells as compared to CTRL cells. c Heatmap of the Top100 differentially regulated genes (sorted by adjusted p-value, based on rlog normalized counts) in NCH644. Hierarchical clustering separates control cells and knockdown cells efficiently. d Heatmap of the Top100 differentially regulated genes (sorted by adjusted p-value, based on rlog normalized counts) in NCH421k. Hierarchical clustering separates control cells and knockdown cells efficiently

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BMC Cancer

ISSN: 1471-2407

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