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Table 1 Clinical characteristics of patients in the full cohort, the Right-sided cohort, and the Left-sided cohort

From: Prognostic value of total number of lymph nodes retrieved differs between left-sided colon cancer and right-sided colon cancer in stage III patients with colon cancer

Patients characteristics Full cohort
(N = 63,243
Right-sided
(N = 39,024)
Left-sided
(N = 24,219)
Total number of lymph nodes < 12 Total number of lymph nodes ≥12 Total number of lymph nodes < 12 Total number of lymph nodes ≥12 Total number of lymph nodes < 12 Total number of lymph nodes ≥12
  16,127 (25.5%) 47,116 (74.5%) 8370 (21.4%) 30,654 (78.6%) 7757 (32.0%) 16,462 (68.0%)
Age at diagnosis
  < 40 277 (1.7%) 1800 (3.8%) 93 (1.1%) 885 (2.9%) 184 (2.4%) 915 (5.6%)
 40–49 872 (5.4%) 3631 (7.7%) 291 (3.5%) 1792 (5.8%) 581 (7.5%) 1839 (11.2%)
 50–59 2473 (15.3%) 8658 (18.4%) 889 (10.6%) 4658 (15.2%) 1584 (20.4%) 4000 (24.3%)
 60–69 3664 (22.7%) 10,934 (23.2%) 1719 (20.5%) 6984 (22.8%) 1945 (25.1%) 3950 (24.0%)
  > 70 8841 (54.8%) 22,093 (46.9%) 5378 (64.3%) 16,335 (53.3%) 3463 (44.6%) 5758 (35.0%)
Gender
 Male 8011 (49.7%) 22,422 (47.6%) 3828 (45.7%) 13,797 (45.0%) 4183 (53.9%) 8625 (52.4%)
 Female 8116 (47.6%) 24,694 (52.4%) 4542 (54.3%) 16,857 (55.0%) 3574 (46.1%) 7837 (47.6%)
Race
 Black 2144 (13.3%) 5796 (12.3%) 1113 (13.3%) 3805 (12.4%) 1031 (34.1%) 1991 (12.1%)
 White 12,446 (77.2%) 37,081 (78.7%) 6691 (79.9%) 24,651 (80.4%) 5755 (74.2%) 12,430 (75.5%)
 Hispanic/Latino 119 (0.7%) 296 (0.6%) 69 (0.8%) 181 (0.6%) 50 (0.6%) 115 (0.7%)
 Asian or Pacific Islander and others 1378 (8.5%) 3784 (8.0%) 484 (5.8%) 1922 (6.3%) 894 (11.5%) 1862 (11.3%)
 Unknown 40 (0.2%) 159 (0.3%) 13 (0.2%) 95 (0.3%) 27 (0.3%) 64 (0.4%)
Hispanic
 No 14,460 (89.7%) 42,480 (90.2%) 7579 (90.5%) 27,800 (90.7%) 6881 (88.7%) 14,680 (89.2%)
 Yes 1667 (10.3%) 4636 (9.8%) 791 (9.5%) 2854 (9.3%) 876 (11.3%) 1782 (10.8%)
T stage
 T0–T2 (0, 2, 3) 2723 (16.9%) 5553 (11.8%) 1144 (13.7%) 3437 (11.2%) 1579 (20.4%) 2116 (12.9%)
 T3–T4 (4, 5) 13,376 (82.9%) 41,503 (88.1%) 7216 (86.2%) 27,181 (88.7%) 6160 (79.4%) 14,322 (87.0%)
 TX (6) 28 (0.2%) 60 (0.1%) 10 (0.1%) 36 (0.1%) 18 (0.2%) 24 (0.1%)
N stage
 N1 12,005 (74.4%) 29,678 (63.0%) 6057 (72.4%) 19,100 (62.3%) 5948 (76.7%) 1809 (23.3%)
 N2 4122 (25.6%) 17,438 (37.0%) 2313 (27.6%) 11,554 (37.7%) 10,578 (64.3%) 5884 (35.7%)
Chemotherapy
 No 8200 (50.8%) 19,558 (41.5%) 4640 (55.4%) 13,549 (44.6%) 3560 (45.9%) 6009 (36.5%)
 Yes 7927 (49.2%) 27,558 (58.5%) 3730 (44.6%) 17,105 (55.8%) 4197 (54.1%) 10,453 (63.5%)
Radiotherapy
 No 37 (0.2%) 88 (0.2%) 18 (0.2%) 57 (0.2%) 19 (0.2%) 31 (0.2%)
 Yes 343 (2.1%) 868 (1.8%) 107 (1.3%) 298 (1.0%) 236 (3.0%) 570 (3.5%)
 Unknown 15,747 (97.6%) 46,160 (98.0%) 8245 (98.5%) 30,299 (98.8%) 7502 (96.7%) 15,861 (96.3%)
Marital status
 Single, separated, divorced, 3574 (22.2%) 11,237 (23.8%) 1734 (20.7%) 6932 (22.6%) 1840 (23.7%) 4305 (26.2%)
 Married (including common law) 8568 (53.1%) 25,176 (53.4%) 4223 (50.5%) 15,937 (52.0%) 4345 (56.0%) 9239 (56.1%)
 Widowed 3362 (20.8%) 8714 (18.5%) 2053 (24.5%) 6469 (21.1%) 1309 (16.9%) 2245 (13.6%)
 Unknown 623 (3.9%) 1989 (4.2%) 360 (4.3%) 1316 (4.3%) 263 (3.4%) 673 (4.1%)
Pathology grade
 Well-differentiated 999 (6.2%) 2440 (5.2%) 483 (5.8%) 1539 (5.0%) 516 (6.7%) 901 (5.5%)
 Moderately differentiated 10.677 (66.2%) 29,917 (63.5%) 5042 (60.2%) 18,005 (58.7%) 5635 (72.6%) 11,912 (72.4%)
 Poorly differentiated 3619 (22.4%) 11,956 (25.4%) 2338 (27.9%) 8995 (29.3%) 1281 (16.5%) 2961 (18.0%)
 Undifferentiated 401 (2.5%) 1802 (3.8%) 274 (3.3%) 1431 (4.7%) 127 (1.6%) 371 (2.3%)
 Unknown 431 (2.7%) 1.001 (2.1%) 233 (2.8%) 684 (2.2%) 198 (2.6%) 317 (1.9%)
Positive lymph node
 0 421 (2.6%) 971 (2.1%) 193 (2.3%) 576 (1.9%) 228 (2.9%) 395 (2.4%)
 1 6032 (37.4%) 14,198 (30.1%) 3050 (36.4%) 9165 (29.9%) 2982 (38.4%) 5033 (30.6%)
 2–3 5483 (34.0%) 14,244 (30.2%) 2776 (33.2%) 9176 (29.9%) 2707 (34.9%) 5068 (30.8%)
 4–6 3023 (18.7%) 9226 (19.6%) 1621 (19.4%) 6008 (19.6%) 1402 (18.1%) 3218 (19.5%)
  ≥ 7 1168 (7.2%) 8477 (18.0%) 730 (8.7%) 5729 (18.7%) 438 (5.6%) 2748 (16.7%)
Lymph nodes ratio
  < 0.07 421 (2.6%) 14,484 (30.7%) 193 (2.3%) 9518 (31.0%) 228 (2.9%) 4966 (30.2%)
 0.07–0.25 7089 (44.0%) 20,189 (42.8%) 3673 (43.9%) 12,965 (42.3%) 3416 (44.0%) 7224 (43.9%)
 0.25–0.50 4645 (28.8%) 7954 (16.9%) 2361 (28.2%) 5172 (16.9%) 2284 (29.4%) 2782 (16.9%)
 0.50–1.0 3972 (24.6%) 4489 (9.5%) 2143 (25.6%) 2999 (9.8%) 1829 (23.6%) 1490 (9.1%)
Tumor site
 Right-sided 8370 (51.9%) 30,654 (65.1%)     
 Left-sided 7757 (48.1%) 16,462 (34.9%)