Clinically significant association of elevated expression of nuclear factor E2-related factor 2 expression with higher glucose uptake and progression of upper urinary tract cancer

Table 2 Cox regression analysis for various potential prognostic factors in overall survival

Variable	Unfavorable/ favorable characteristics	No. of Patients	Univariate (U)			Multivariate (M)
Variable	Unfavorable/ favorable characteristics	No. of Patients	Relative risk	95% confidential interval	P value	Relative risk	95% confidential interval	P value
Grade	3 / 2 / 1	42 / 54 / 11	1.868	1.086–3.211	0.0239	1.047	0.345–1.219	0.1399
pT	4 / 3 / 2 / 1	12 / 38 / 35 / 22	2.762	1.855–4.113	< 0.0001	1.814	1.041–3.160	0.0355
pN	2,1 / 0	18 / 89	3.030	1.985–4.626	< 0.0001	1.912	1.210–3.020	0.0055
lymphovascular invasion (LVI)	1 / 0	64 / 43	11.175	3.981–31.365	< 0.0001	5.451	1.364–21.795	0.0165
Nrf2	high / low	53 / 54	4.063	2.119–7.792	< 0.0001	2.242	1.040–4.832	0.0393

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