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Table 2 Cox regression analysis for various potential prognostic factors in overall survival

From: Clinically significant association of elevated expression of nuclear factor E2-related factor 2 expression with higher glucose uptake and progression of upper urinary tract cancer

Variable Unfavorable/ favorable characteristics No. of Patients Univariate (U) Multivariate (M)
Relative risk 95% confidential interval P value Relative risk 95% confidential interval P value
Grade 3 / 2 / 1 42 / 54 / 11 1.868 1.086–3.211 0.0239 1.047 0.345–1.219 0.1399
pT 4 / 3 / 2 / 1 12 / 38 / 35 / 22 2.762 1.855–4.113 < 0.0001 1.814 1.041–3.160 0.0355
pN 2,1 / 0 18 / 89 3.030 1.985–4.626 < 0.0001 1.912 1.210–3.020 0.0055
lymphovascular invasion (LVI) 1 / 0 64 / 43 11.175 3.981–31.365 < 0.0001 5.451 1.364–21.795 0.0165
Nrf2 high / low 53 / 54 4.063 2.119–7.792 < 0.0001 2.242 1.040–4.832 0.0393