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Table 2 Details of trials included in IAC treatment based on ICRB grading

From: Comparison between intravenous chemotherapy and intra-arterial chemotherapy for retinoblastoma: a meta-analysis

Authors

Mean follow -up

(months)

Globe salvage in different group eyes (%)

Overall Success Rate (%)

Second Tumor Rate (%)

Metastasis

Rate (%)

Recurrence Rate (%)

Secondary treatment success rate (%)

A

(n = 0)

B

(n = 12)

C

(n = 17)

D

(n = 148)

E

(n = 49)

Thampi2013

14.5

85.7(6/7)

38.5(5/13)

55.0(11/20)

NA

0.0(0/20)

NA

NA

Gobin2011

24.0

NA

NA

NA

NA

NA

81.7(35/43)

NA

NA

NA

58.4(30/52)

Abramson2016

34.0

NA

NA

NA

85.1(40/47)

NA

78.6(88/112)

0.0(0/112)

2.7(3/112)

NA

72.4(42/58)

Shields2014

19.0

NA

100.0(1/1)

100.0(4/4)

94.1(16/17)

35.7(5/14)

72.2(26/36)

NA

0.0(0/70)

NA

61.8(21/34)

Chen2017

13.6

NA

100.0(11/11)

100.0(11/11)

78.6(44/56)

62.1(18/29)

78.5(84/107)

NA

NA

11.2(12/107)

79.0(49/62)

Tuncer2016

29.0

NA

NA

NA

66.6(16/24)

NA

NA

NA

NA

29.2(7/24)

NA

Shields2011

18.0

NA

NA

100.0(2/2)

100.0(4/4)

33.3(2/6)

66.7(8/12)

0.0(0/16)

0.0(0/16)

18.8(3/16)

50.0(2/4)

Fabian2017

38.7

NA

NA

NA

NA

NA

NA

NA

0.0(0/77)

1.3(1/77)

NA

Munier2017

NA

NA

NA

NA

NA

NA

NA

NA

NA

24.0(6/25)

NA

  1. Note: Globe salvage: avoidance of enucleation or EBRT. Abbreviations: IAC = intra-arterial chemotherapy; NA = not applicable