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Table 3 Proportion of patients in each treatment arm by current dose step at each time

From: A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment

Time Dose step Single agent (haloperidol) Guideline therapy Total Chi-square, p-value
N n (%) N n (%) N n (%)
24 h Step 1 82 82 (100) 92 92(100) 174 174 (100)  
48 ha Step 1   28 (37.3)   45 (54.2)   74 (46.5)  
Step 2 75 47 (62.7) 83 38 (45.8) 158 85 (53.5) Χ2 = 4.5, p = 0.03
72 h Step 1 75 23 (30.7) 74 36 (48.4) 149 59 (39.6)  
Step 2 30 (40.0) 25 (33.8) 55 (36.9) Χ2 = 5.6,
Step 3 22 (29.3) 13 (17.6) 35 (23.5) p = 0.06
  1. aOne patient on Step 1 escalated to Step 3 due to rescue medications given