Skip to main content

Table 3 Proportion of patients in each treatment arm by current dose step at each time

From: A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment

Time

Dose step

Single agent (haloperidol)

Guideline therapy

Total

Chi-square, p-value

N

n (%)

N

n (%)

N

n (%)

24 h

Step 1

82

82 (100)

92

92(100)

174

174 (100)

 

48 ha

Step 1

 

28 (37.3)

 

45 (54.2)

 

74 (46.5)

 

Step 2

75

47 (62.7)

83

38 (45.8)

158

85 (53.5)

Χ2 = 4.5, p = 0.03

72 h

Step 1

75

23 (30.7)

74

36 (48.4)

149

59 (39.6)

 

Step 2

30 (40.0)

25 (33.8)

55 (36.9)

Χ2 = 5.6,

Step 3

22 (29.3)

13 (17.6)

35 (23.5)

p = 0.06

  1. aOne patient on Step 1 escalated to Step 3 due to rescue medications given