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Fig. 2 | BMC Cancer

Fig. 2

From: HPV-16 E7 expression up-regulates phospholipase D activity and promotes rapamycin resistance in a pRB-dependent manner

Fig. 2

pRb downregulation leads to PLD activation in PHK. a Expression of pRb in PHK was silenced using lentiviral particles codifying specific shRNAs. Silencing efficiency was determined by western blot in 30 micrograms of total protein extracts. b The effect of pRb silencing on PLD activity was determined using Phospholipase D kit according to manufacture instructions. Error bars represent the standard deviation for three independent experiments. (*) p < 0.05

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BMC Cancer

ISSN: 1471-2407

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