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Fig. 3 | BMC Cancer

Fig. 3

From: Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells

Fig. 3

CICs demonstrate reduced expression of MHC-I. a MHC-I change in mean fluorescent intensity (Δ-MFI) between non-CICs and CICs for TC-1 cells demonstrates reduced expression of MHC-I on CICs, n = 8. b HLA-ABC Δ-MFI between non-CICs (filled) and CICs (open) for human lung cancer cell lines demonstrates a decrease in HLA-ABC for CICs compared to non-CICs for five out of six cell lines, n = 3–4. Error bars are standard deviation. ***P ≤ 0.001, **P = 0.003, *P = 0.018

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