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Table 3 Reasons for dose reduction

From: Chemotherapy for metastatic colon cancer: No effect on survival when the dose is reduced due to side effects

Distribution of adverse effects

N

%

Leukopenia

20

30%

Polyneuropathy

11

16%

Diarrhea

10

14%

Worsening of general condition

6

9%

Hand-foot-syndrome

5

7%

Thrombocytopenia

5

7%

Hyperemesis

3

4%

Elevated bilirubin

2

3%

Deterioration of kidney function

1

1%

Mucositis

1

1%

Not specified

5

7%