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Table 3 Reasons for dose reduction

From: Chemotherapy for metastatic colon cancer: No effect on survival when the dose is reduced due to side effects

Distribution of adverse effects N %
Leukopenia 20 30%
Polyneuropathy 11 16%
Diarrhea 10 14%
Worsening of general condition 6 9%
Hand-foot-syndrome 5 7%
Thrombocytopenia 5 7%
Hyperemesis 3 4%
Elevated bilirubin 2 3%
Deterioration of kidney function 1 1%
Mucositis 1 1%
Not specified 5 7%