Table 3 Prognostic factors for DFS and OS by univariate analysis
Variables | n | DFS | P | OS | P | ||||
|---|---|---|---|---|---|---|---|---|---|
1-yr | 3-yrs | 5-yrs | 1-yr | 3-yrs | 5-yrs | ||||
Sex | |||||||||
Male | 68 | 47.1% | 36.8% | 30.5% | 0.433 | 79.4% | 50.0% | 41.2% | 0.478 |
Female | 16 | 56.3% | 37.5% | 37.5% | 87.5% | 56.3% | 50.0% | ||
Age(yrs) | |||||||||
< 60 | 68 | 45.6% | 32.4% | 27.7% | 0.104 | 82.4% | 48.5% | 39.7% | 0.391 |
≥ 60 | 16 | 62.5% | 56.3% | 49.2% | 75.0% | 62.5% | 56.3% | ||
PLT(×109) | |||||||||
<100 | 10 | 80.0% | 60.0% | 60.0% | 0.053 | 100% | 80.0% | 70.0% | 0.076 |
≥ 100 | 74 | 44.6% | 33.8% | 28.0% | 78.4% | 47.3% | 39.2% | ||
HbsAg | |||||||||
Positive | 72 | 47.2% | 38.9% | 33.0% | 0.700 | 79.2% | 50.0% | 44.4% | 0.882 |
Negative | 12 | 58.3% | 25.0% | 25.0% | 91.7% | 58.3% | 33.3% | ||
AFP(μg/L) | |||||||||
<20 | 36 | 52.8% | 38.9% | 38.9% | 0.336 | 83.3% | 50.0% | 44.4% | 0.750 |
≥ 20 | 48 | 45.8% | 35.4% | 26.3% | 79.2% | 52.1% | 41.7% | ||
Ascites | |||||||||
No | 68 | 52.9% | 39.7% | 35.0% | 0.093 | 83.8% | 51.5% | 44.1% | 0.551 |
Yes | 16 | 31.3% | 25.0% | 18.8% | 68.8% | 50.0% | 37.5% | ||
Cirrhosis | |||||||||
No | 24 | 45.0% | 35.0% | 30.0% | 0.685 | 95.0% | 60.0% | 45.0% | 0.485 |
Yes | 60 | 50.0% | 37.5% | 32.4% | 76.6% | 48.4% | 42.2% | ||
Tumor number | |||||||||
Single | 62 | 59.7% | 43.5% | 36.7% | 0.002 | 85.5% | 61.3% | 51.6% | < 0.001 |
Multiple | 22 | 18.2% | 18.2% | 18.2% | 68.2% | 22.7% | 18.2% | ||
PVTT | |||||||||
No | 73 | 54.8% | 41.1% | 35.3% | < 0.001 | 87.7% | 56.2% | 47.9% | < 0.001 |
Yes | 11 | 9.1% | 9.1% | 9.1% | 36.4% | 18.2% | 9.1% | ||
Tumor size (cm) | |||||||||
< 5 | 34 | 64.7% | 47.1% | 41.2% | 0.055 | 97.1% | 67.6% | 52.9% | 0.040 |
≥ 5 | 50 | 38.0% | 30.0% | 25.7% | 70.0% | 40.0% | 36.0% | ||
Tumor Encapsulation | |||||||||
None | 20 | 30.0% | 25.0% | 15.0% | 0.013 | 60.0% | 45.0% | 30.0% | 0.081 |
Complete | 64 | 54.7% | 40.6% | 37.3% | 87.5% | 53.1% | 46.9% | ||
Resection margin | |||||||||
<2 cm | 45 | 40.0% | 26.7% | 24.4% | 0.106 | 80.0% | 40.0% | 28.9% | 0.007 |
≥ 2 cm | 39 | 59.0% | 48.7% | 40.5% | 82.1% | 64.1% | 59.0% | ||
Complication | |||||||||
No | 73 | 49.3% | 38.4% | 32.8% | 0.407 | 84.9% | 53.4% | 45.2% | 0.095 |
Yes | 11 | 45.5% | 27.3% | 27.3% | 54.5% | 36.4% | 27.3% | ||
Tumor differetiation | |||||||||
I-II | 62 | 54.8% | 41.9% | 35.0% | 0.212 | 85.5% | 56.5% | 48.4% | 0.037 |
III-IV | 22 | 31.8% | 22.7% | 22.7% | 68.2% | 36.4% | 27.3% | ||
Blood inflow occlusion | |||||||||
Yes | 31 | 41.9% | 29.0% | 20.7% | 0.182 | 77.4% | 48.4% | 35.5% | 0.300 |
No | 53 | 52.8% | 41.5% | 37.7% | 83.0% | 52.8% | 47.2% | ||
Blood transfusion | |||||||||
Yes | 25 | 20.0% | 4.0% | 4.0% | < 0.001 | 56.0% | 12.0% | 4.0% | < 0.001 |
No | 59 | 61.0% | 50.8% | 43.7% | 91.5% | 67.8% | 59.3% | ||
Blood loss (mL) | |||||||||
≤ 1000 | 73 | 54.8% | 42.5% | 36.7% | < 0.001 | 86.3% | 58.9% | 49.3% | < 0.001 |
> 1000 | 11 | 9.1% | 0.0% | 0.0% | 45.5% | 0.0% | 0.0% | ||
Operative time(min) | |||||||||
≤ 180 | 42 | 66.7% | 54.8% | 47.3% | < 0.001 | 92.9% | 73.8% | 64.3% | < 0.001 |
> 180 | 42 | 31.0% | 19.0% | 16.7% | 69.0% | 28.6% | 21.4% | ||
TNM stage | |||||||||
I | 55 | 60.0% | 43.6% | 39.7% | 0.002 | 90.9% | 60.0% | 52.7% | 0.001 |
II-III | 29 | 27.6% | 24.1% | 17.2% | 62.1% | 34.5% | 24.1% | ||
c-Myc | |||||||||
Low | 34 | 17.6% | 11.8% | 11.8% | < 0.001 | 64.7% | 20.6% | 14.7% | < 0.001 |
High | 50 | 70.0% | 54.0% | 45.9% | 92.0% | 72.0% | 62.0% | ||