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Table 3 Prognostic factors for DFS and OS by univariate analysis

From: Low expression of c-Myc protein predicts poor outcomes in patients with hepatocellular carcinoma after resection

Variables n DFS P OS P
1-yr 3-yrs 5-yrs 1-yr 3-yrs 5-yrs
Sex
 Male 68 47.1% 36.8% 30.5% 0.433 79.4% 50.0% 41.2% 0.478
Female 16 56.3% 37.5% 37.5% 87.5% 56.3% 50.0%
Age(yrs)
  < 60 68 45.6% 32.4% 27.7% 0.104 82.4% 48.5% 39.7% 0.391
  ≥ 60 16 62.5% 56.3% 49.2% 75.0% 62.5% 56.3%
PLT(×109)
 <100 10 80.0% 60.0% 60.0% 0.053 100% 80.0% 70.0% 0.076
  ≥ 100 74 44.6% 33.8% 28.0% 78.4% 47.3% 39.2%
HbsAg
 Positive 72 47.2% 38.9% 33.0% 0.700 79.2% 50.0% 44.4% 0.882
 Negative 12 58.3% 25.0% 25.0% 91.7% 58.3% 33.3%
AFP(μg/L)
 <20 36 52.8% 38.9% 38.9% 0.336 83.3% 50.0% 44.4% 0.750
  ≥ 20 48 45.8% 35.4% 26.3% 79.2% 52.1% 41.7%
Ascites
 No 68 52.9% 39.7% 35.0% 0.093 83.8% 51.5% 44.1% 0.551
 Yes 16 31.3% 25.0% 18.8% 68.8% 50.0% 37.5%
Cirrhosis
 No 24 45.0% 35.0% 30.0% 0.685 95.0% 60.0% 45.0% 0.485
 Yes 60 50.0% 37.5% 32.4% 76.6% 48.4% 42.2%
Tumor number
 Single 62 59.7% 43.5% 36.7% 0.002 85.5% 61.3% 51.6% < 0.001
 Multiple 22 18.2% 18.2% 18.2% 68.2% 22.7% 18.2%
PVTT
 No 73 54.8% 41.1% 35.3% < 0.001 87.7% 56.2% 47.9% < 0.001
 Yes 11 9.1% 9.1% 9.1% 36.4% 18.2% 9.1%
Tumor size (cm)
  < 5 34 64.7% 47.1% 41.2% 0.055 97.1% 67.6% 52.9% 0.040
  ≥ 5 50 38.0% 30.0% 25.7% 70.0% 40.0% 36.0%
Tumor Encapsulation
 None 20 30.0% 25.0% 15.0% 0.013 60.0% 45.0% 30.0% 0.081
 Complete 64 54.7% 40.6% 37.3% 87.5% 53.1% 46.9%
Resection margin
 <2 cm 45 40.0% 26.7% 24.4% 0.106 80.0% 40.0% 28.9% 0.007
  ≥ 2 cm 39 59.0% 48.7% 40.5% 82.1% 64.1% 59.0%
Complication
 No 73 49.3% 38.4% 32.8% 0.407 84.9% 53.4% 45.2% 0.095
 Yes 11 45.5% 27.3% 27.3% 54.5% 36.4% 27.3%
Tumor differetiation
 I-II 62 54.8% 41.9% 35.0% 0.212 85.5% 56.5% 48.4% 0.037
 III-IV 22 31.8% 22.7% 22.7% 68.2% 36.4% 27.3%
Blood inflow occlusion
 Yes 31 41.9% 29.0% 20.7% 0.182 77.4% 48.4% 35.5% 0.300
 No 53 52.8% 41.5% 37.7%   83.0% 52.8% 47.2%  
Blood transfusion
 Yes 25 20.0% 4.0% 4.0% < 0.001 56.0% 12.0% 4.0% < 0.001
 No 59 61.0% 50.8% 43.7%   91.5% 67.8% 59.3%  
Blood loss (mL)
  ≤ 1000 73 54.8% 42.5% 36.7% < 0.001 86.3% 58.9% 49.3% < 0.001
  > 1000 11 9.1% 0.0% 0.0%   45.5% 0.0% 0.0%  
Operative time(min)
  ≤ 180 42 66.7% 54.8% 47.3% < 0.001 92.9% 73.8% 64.3% < 0.001
  > 180 42 31.0% 19.0% 16.7%   69.0% 28.6% 21.4%  
TNM stage
 I 55 60.0% 43.6% 39.7% 0.002 90.9% 60.0% 52.7% 0.001
 II-III 29 27.6% 24.1% 17.2% 62.1% 34.5% 24.1%
c-Myc
 Low 34 17.6% 11.8% 11.8% < 0.001 64.7% 20.6% 14.7% < 0.001
 High 50 70.0% 54.0% 45.9% 92.0% 72.0% 62.0%
  1. AFPAlpha-fetoprotein, ALT alanine aminotransferase, HBsAg hepatitis B surface antigen, PLT platelet, PVTT portal vein tumor thrombi