Fig. 6
From: Small cell and non small cell lung cancer form metastasis on cellular 4D lung model

Metastatic lesion formation. Among NSCLC, H1299, a metastatic p53 mutant cell formed significantly more metastatic lesions as compared to A549 cells (a; b vs d) per high power field (HPF). H460 cells also formed metastatic lesions (a and c). Among SCLC cell lines, H69 formed more metastatic lesions than H446 and SHP-77 (e–h). In breast cancer cells, MDAMB231, a triple negative cell line, formed significantly more metastatic lesions than MCF-7 cells (i–k)