Fig. 1
From: Small cell and non small cell lung cancer form metastasis on cellular 4D lung model
Cellular ex vivo 4D lung model in a bioreactor without any tumor cells (control). Bioreactor showing connection from the lung to oxygenator and pump in cell culture incubator (a). The lung after 15 days in the bioreactor is intact (b). H&E staining shows intact alveoli, bronchus and vasculature (c) with some apoptotic cells. CD34 staining shows the endothelial lining in intact vasculature (e) and Movat pentachrome staining represents the components of extracellular matrix (f)