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Table 1 After expansion by Pearson, the 41 genes correlated with the rest 211 genes and involved in 32 pathways

From: Putative cancer stem cells may be the key target to inhibit cancer cell repopulation between the intervals of chemoradiation in murine mesothelioma

Number

Pathway ID

Pathway

FDRa

1

GO:0008299

Isoprenoid biosynthetic process

0.002134

2

GO:0051346

Negative regulation of hydrolase activity

0.002385

3

GO:0006644

Phospholipid metabolic process

0.003211

4

GO:0006916

Anti-apoptosis

0.00327

5

GO:0043086

Negative regulation of catalytic activity

0.003652

6

GO:0042976

Activation of Janus kinase activity

0.004027

7

GO:0018106

Peptidyl-histidine phosphorylation

0.004027

8

GO:0006417

Regulation of translation

0.006019

9

GO:0031399

Regulation of protein modification process

0.006455

10

GO:0010608

Posttranscriptional regulation of gene expression

0.006471

11

GO:0031124

mRNA 3'-end processing

0.006525

12

GO:0040008

Regulation of growth

0.007398

13

GO:0008202

Steroid metabolic process

0.007429

14

GO:0008361

Regulation of cell size

0.007517

15

GO:0045793

Positive regulation of cell size

0.007545

16

GO:0045927

Positive regulation of growth

0.007662

17

GO:0006066

Alcohol metabolic process

0.007722

18

GO:0001932

Regulation of protein phosphorylation

0.00775

19

GO:0043154

Negative regulation of caspase activity

0.007818

20

GO:0016049

Cell growth

0.007857

21

GO:0043066

Negative regulation of apoptosis

0.007891

22

GO:0008610

Lipid biosynthetic process

0.007913

23

GO:0030307

Positive regulation of cell growth

0.008

24

GO:0007259

JAK-STAT cascade

0.008302

25

GO:0060548

Negative regulation of cell death

0.009413

26

GO:0001558

Regulation of cell growth

0.00978

27

GO:0043069

Negative regulation of programmed cell death

0.009786

28

GO:0051336

Regulation of hydrolase activity

0.009791

29

GO:0016126

Sterol biosynthetic process

0.01

30

GO:0008203

Cholesterol metabolic process

0.01

31

GO:0006695

Cholesterol biosynthetic process

0.01

32

GO:0016125

Sterol metabolic process

0.01

  1. At cutoffs of 0.98<r<-0.98 and p<0.00001, 221 genes were identified to be significantly correlated with one of the 41 genes. aFDR False discovery rate. FDR<0.01