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Table 1 Five normal tissue complication probability (NTCP) models from four published and present study

From: Development of a normal tissue complication probability (NTCP) model for radiation-induced hypothyroidism in nasopharyngeal carcinoma patients

NTCP model b constant OR 95% CI AUC
Boomsma et al.   0.011    0.85 (95% CI: 0.78–0.92)
 Dmean 0.062   1.064/Gy 1.029–1.101  
 Thyroid volume −0.19   0.826/cm3 0.740–0.921  
Cella et al. model 1   −1.83    0.865 (95% CI: 0.793–0.945)
 V30% 0.038   1.039 1.019–1.059  
 Gender −2.32   0.098 0.019–0.500  
Cella et al. model 2   1.94    0.874 (95% CI: 0.750–0.951)
 V30 cc 0.26   1.297 1.087–1.547  
 Gender −2.21   0.110 0.021–0.580  
 Thyroid volume −0.27   0.763 0.615–0.947  
Rønjom et al.   −2.019    NA
 Dmean 0.0821   1.12/Gy 1.07–1.20  
 Thyroid volume −0.189   0.75/cm3 0.64–0.85  
Luo et al.   −2.695    0.793(95% CI: 0.725–0.851)
 V50 0.050   1.051 1.027–1.076  
 Pmax −0.026   0.974 0.956–0.993  
 Gender 1.280   3.598 1.461–8.865  
 Chemotherapy 2.902   18.213 1.920–172.766  
  1. Abbreviation: OR odds ratio, CI confidence interval, AUC the area under the receiver operating characteristic curve, NA not available in original article