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Table 1 Characteristics of the microRNAs mentioned in the literature

From: Serum microRNA signatures and metabolomics have high diagnostic value in gastric cancer

MicroRNA Expression GC sample size Control sample size Sensitivity (%) Specificity (%) AUC Number of included articles
miR-451 U 144 172 91.2 96.5 0.980 2
miR-183 U 76 26 93.4 92.3 0.978 1
miR-300 U 25 15 96.0 86.7 NA 1
miR-940 D 110 100 73.2 97.9 0.970 1
miR-486 U 144 172 78.1 94.0 0.950 2
miR-421 U 130 107 92.3 79.4 0.940 2
miR-100 U 90 87 86.9 87.3 0.930 2
miR-19a U 215 241 83.1 89.5 0.930 3
miR-19b U 215 241 76.6 88.4 0.910 3
miR-627 U 108 96 80.0 89.6 0.900 1
miR-21 U & D 334 250 77.8 87.3 0.900 6
miR-204 D 94 100 73.4 82.6 0.896 1
miR-206 D 150 150 78.0 86.0 0.890 1
miR-200c U & D 233 145 81.8 81.8 0.890 4
miR-503 D 68 32 96.8 79.4 0.889 1
miR-26a D 280 280 83.6 81.5 0.882 1
miR-17-3p U 154 180 69.7 88.9 0.880 2
miR-652 U 108 96 65.7 88.8 0.880 1
miR-130a U 41 41 77.9 90.2 0.870 1
miR-629 U 108 96 85.2 82.0 0.870 1
miR-196a U 98 126 69.5 97.6 0.864 1
miR-378 U 40 41 87.5 70.7 0.861 1
miR-101 U 58 60 71.0 88.1 0.857 1
miR-233 U 50 47 81.0 78.0 0.850 1
miR-106b U 314 275 72.0 84.3 0.850 4
miR-142-3p D 280 280 74.4 84.1 0.839 1
miR-192 U 29 10 75.9 90.0 0.833 1
miR-18a U 500 439 73.2 80.8 0.830 6
miR-199a U 415 296 78.1 74.3 0.830 4
miR-6503-5p U 361 103 57.9 88.3 0.830 2
miR-200b D 84 30 62.7 93.4 0.826 1
miR-92a U 382 665 75.0 77.6 0.820 5
miR-20a U 615 557 71.8 77.8 0.820 6
miR-223 U 211 211 70.8 78.7 0.820 4
miR-196b U 98 126 62.2 96.1 0.811 1
miR-16 U 138 189 76.6 87.6 0.810 2
miR-25 U 634 431 67.6 83.5 0.810 5
miR-1 U 240 166 79.2 73.2 0.800 2
miR-375 D 91 91 75.3 73.6 0.800 3
miR-140-5p U 108 96 81.7 70.0 0.790 1
miR-106a U & D 287 159 70.0 79.7 0.790 4
miR-744 U 287 228 75.7 72.0 0.790 2
miR-210 U 201 191 76.8 63.9 0.780 2
miR-181b U 46 21 77.2 72.7 0.770 1
miR-27a U 149 124 71.8 70.8 0.770 3
miR-17-5p U & D 313 237 55.3 80.4 0.770 4
miR-195 D 280 280 69.2 75.4 0.765 1
miR-222 U 182 124 62.3 82.6 0.760 2
miR-148a D 331 331 60.2 76.2 0.760 2
miR-93 U 65 65 81.5 73.8 0.756 1
miR-218 D 60 60 94.3 44.3 0.743 1
miR-23b U & D 184 104 71.3 88.9 0.730 2
miR-191 U 125 126 61.8 97.6 0.730 2
miR-215 U 29 10 62.1 88.3 0.724 1
miR-371-5p U 40 41 75.0 63.4 0.715 1
miR-376c U 68 68 74.0 62.7 0.710 1
miR-187* U 40 41 82.5 61.0 0.704 1
let-7e U 68 68 62.1 79.2 0.700 1
miR-320a D 35 38 65.2 68.2 0.699 1
miR-92b U 101 91 46.9 88.2 0.690 1
miR-221 U 248 248 63.1 92.1 0.670 3
miR-27b U 68 68 48.7 82.0 0.660 1
miR-107 U & N 86 86 40.7 80.2 0.660 2
miR-185 U 101 91 46.7 84.9 0.650 1
miR-34a U 180 106 59.4 67.8 0.645 1
miR-151-5p U 180 80 61.0 57.0 0.625 1
miR-423-5p U 180 106 87.3 31.6 0.590 1
miR-103 N 50 50 93.6 24.4 0.548 1
miR-425 U 57 58 31.7 84.2 0.548 1
miR-194 N 50 50 94.2 24.4 0.512 1
  1. We use U to represent the upregulated expression, use D to represent the downregulated expression and use N to represent no significant difference in the GC patients versus the control group. The data on the sensitivity, specificity and AUC were obtained via the meta-analysis when the number of included articles was more than one
  2. Abbreviations: GC gastric cancer, AUC area under the curve, NA not available
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