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Table 2 Multivariate regression tests upon up-staging to pathologic stage T3a in 3431 patients surgically treated for localized renal cell carcinoma

From: Outcomes of pathologic stage T3a renal cell carcinoma up-staged from small renal tumor: emphasis on partial nephrectomy

 

Adjusted with hilar location

Adjusted with tumour shape

HR

95% CI

p value

HR

95% CI

p value

Age

1.032

1.018–1.046

<  0.001

1.032

1.017–1.046

<  0.001

High BMI (≥24 kg/m2)

0.871

0.641–1.184

0.379

0.870

0.640–1.182

0.373

Gender (Female)

0.766

0.543–1.079

0.127

0.767

0.544–1.081

0.129

Diabetes mellitus (yes)

1.313

0.890–1.939

0.170

1.316

0.891–1.942

0.167

Hypertension (yes)

1.127

0.811–1.567

0.476

1.128

0.812–1.568

0.472

ECOG score (≥2)

0.567

0.238–1.355

0.202

0.575

0.241–1.376

0.214

Tumour size

1.686

1.551–1.834

<  0.001

1.726

1.588–1.877

<  0.001

Hilar location (yes)

1.765

1.147–2.715

0.010

   

Tumour location

 Exophytic

    

Reference

 

 Mesophytic

   

0.805

0.539–1.202

0.288

 Endophytic

   

1.318

0.925–1.879

0.126

  1. HR hazard ratio, CI confidence interval, BMI body mass index, ECOG Eastern Cooperative Oncology Group