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Table 2 Multivariate regression tests upon up-staging to pathologic stage T3a in 3431 patients surgically treated for localized renal cell carcinoma

From: Outcomes of pathologic stage T3a renal cell carcinoma up-staged from small renal tumor: emphasis on partial nephrectomy

  Adjusted with hilar location Adjusted with tumour shape
HR 95% CI p value HR 95% CI p value
Age 1.032 1.018–1.046 <  0.001 1.032 1.017–1.046 <  0.001
High BMI (≥24 kg/m2) 0.871 0.641–1.184 0.379 0.870 0.640–1.182 0.373
Gender (Female) 0.766 0.543–1.079 0.127 0.767 0.544–1.081 0.129
Diabetes mellitus (yes) 1.313 0.890–1.939 0.170 1.316 0.891–1.942 0.167
Hypertension (yes) 1.127 0.811–1.567 0.476 1.128 0.812–1.568 0.472
ECOG score (≥2) 0.567 0.238–1.355 0.202 0.575 0.241–1.376 0.214
Tumour size 1.686 1.551–1.834 <  0.001 1.726 1.588–1.877 <  0.001
Hilar location (yes) 1.765 1.147–2.715 0.010    
Tumour location
 Exophytic      Reference  
 Mesophytic     0.805 0.539–1.202 0.288
 Endophytic     1.318 0.925–1.879 0.126
  1. HR hazard ratio, CI confidence interval, BMI body mass index, ECOG Eastern Cooperative Oncology Group