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Table 1 Expression of ZG16 in normal and diseased colorectal epithelium

From: Loss of ZG16 is associated with molecular and clinicopathological phenotypes of colorectal cancer

Diagnosis

Immunohistochemistry (IHC)

Positive cells %

Number of cases

Normal Colon

strong (+++)

95

n = 30

Polyps-PJS

strong (+++)

95

n = 2

Polyps-JPS

Positive (++) to negative

50

n = 3

TA with LGD

Positive (++) to negative

15

n = 4

TVA with LGD

Positive (+) to negative

10

n = 6

Acute Colitis

Positive (+++)

95

n = 1

CUC without colon cancer

Positive (++) to negative

20

n = 4

CUC with colon cancer

Positive (+) to negative

10

n = 2

Colorectal adenocarcinoma

negative

0

n = 25

Colorectal mucinous adenocarcinoma

negative

0

n = 15

  1. PJS: Peutz-Jeghers syndrome, JPS: juvenile polyposis syndrome, TA: tubulous adenoma, LGD: low grade dysplaxia, TVA: tubulovillous adenoma, CUC: chronic ulcerative colitis