Table 4 Cox univariate analysis for progression-free survival, with a time dependency added to CYFRA 21-1 pre-treatment and post-treatment levels
Univariate analysis | ||
|---|---|---|
HR [95%CI] | p | |
Age at diagnosis (> vs. ≤ 65 years) | 0.95 [0.39;2.33] | 0.91 |
Gender (male/female) | 0.57 [0.17;1.96] | 0.47 |
T stage (T3/T4 vs. T1/T2) | 2.65 [1.06;6.34] | 0.04 |
Nodal status (positive/negative) | 1.07 [0.44;2.62] | 0.88 |
Clinical stage (IIIA/IIIB vs. I/II) | 1.36 [0.52;3.54] | 0.53 |
Chemotherapy associated with radiation therapy (yes/no) | 1.02 [0.37;2.8] | 0.97 |
CYFRA 21-1 levels (elevated /normal) | ||
Pre-treatment | 2.17 [0.64;7.42] | 0.22 |
Post-treatment | 2.64 [1.09;6.36] | 0.03 |