Fig. 4

Safety evaluation of BJOE combined with another agent versus another agent alone by thoracic perfusion for treating MPE.a No difference in incidence rate of liver and renal injury was testified between BJOE combined with other agents and other agents alone; b The incidence of chest pain caused by BJOE combination therapy had the same occurrence probability compared with the other agents alone; c The BJOE combined with other agents had the same incidence of fever with other agents alone. BJOE, brucea javanica oil emulsion; MPE, malignant pleural effusion; OR, odds ratio