Occupational exposure to petroleum-based and oxygenated solvents and hypopharyngeal and laryngeal cancer in France: the ICARE study

Table 5 Association between hypopharyngeal and laryngeal cancers and exposure to combinations of oxygenated solvents

Exposure to oxygenated solvents	Controls n = 2670	Hypopharynx n = 338		Larynx n = 423
	n	n	OR^a [95% CI]	n	OR^a [95% CI]
None	1684	207	1	268	1
Ket	36	9	1.40 [0.57–3.48]	10	1.26 [0.55–2.92]
Alc, Ket	305	45	0.95 [0.63–1.43]	66	1.15 [0.81–1.63]
Alc, Etg	314	29	1.02 [0.63–1.65]	24	0.64 [0.40–1.05]
Alc, Ket, THF	25	10	2.79 [1.12–6.95]	10	2.25 [0.94–5.38]
Alc, Ket, Etg	158	23	0.84 [0.49–1.45]	27	0.86 [0.52–1.41]

Abbreviations: OR odds-ratio, CI confidence intervals, Ket ketones and esters, Alc alcohols, Etg ethylene glycol, THF tetrahydrofuran
^aOR adjusted for age at interview, residence area, alcohol consumption, smoking status, frequency and duration of smoking, exposure to asbestos

ISSN: 1471-2407