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Table 1 Overview of exemplary models for cancer research

From: In silico cancer research towards 3R

  References
In vivo
Murine models [37]
Genetically engineered mouse model [36]
Zebra fish model [42]
Drosophila model [41]
Chick embryo model [43, 44]
In vitro
General 2D/3D in vitro models [46, 53]
Transwell model [48]
Spheroid system [49]
Microfluidic system [50]
Tissue-engineered microvessel model [51]
In silico
Sequence analysis [63, 69, 74]
General pathway analysis and network inference [132, 133, 135]
Pan-cancer [62, 82, 134, 139]
Chemical perturbation mapping [64, 66, 68]
Pharmacogenomic mapping [99, 102, 117, 136]
Genome-phenotype mapping [81]
Clinical data integration [106]
Structure mapping [102, 103]
Structure and activity [100, 101]
Framework for key events and mode of action [97, 98]
Image classification [85, 87]
Growth prediction [9193]