Fig. 3

G-Rh2 reversed the phenotype of M2 macrophage into M1 subset. a and b M2 macrophages derived from RAW264.7 were treated with different concentrations of G-Rh2 for 24 h. These treated cells were harvested and analyzed through flow cytometry with CD206 marker. c and d M2 macrophages derived from RAW264.7were treated with different concentrations of G-Rh2 for 24 h. These treated cells were harvested and analyzed through flow cytometry with M1 marker CD16/32.The indicated differences are significant: * P < 0.05, **P < 0.01. e and f M2 macrophages derived from THP-1 were treated with different concentrations of G-Rh2 for 24 h. These treated cells were harvested and analyzed through flow cytometry with CD206 marker. g and h M2 macrophages derived from THP-1 were treated with different concentrations of G-Rh2 for 24 h. These treated cells were harvested and analyzed through flow cytometry with M1 marker CD16/32. The indicated differences are significant: * P < 0.05