Skip to main content

Table 1 Association between ADAM-10, ADAM-17, ADAM-28, and FoxM1 expression and clinical variables of hilar cholangiocarcinoma

From: ADAM-17 is a poor prognostic indicator for patients with hilar cholangiocarcinoma and is regulated by FoxM1

Variables N ADAM-10 P ADAM-17 P ADAM-28 P FoxM1 P
Gender
 Male 38 27 0.866 23 0.309 22 0.235 20 0.049
 Female 16 11   12   12   13  
Size
  ≤ 3 cm 21 12 0.089 9 0.007 10 0.063 9 0.028
 >3 cm 33 26   26   24   24  
T stage
 T1–3 7 2 0.009 3 0.192 3 0.238 3 0.288
 T4 47 36   32   31   30  
N stage
 N0 18 10 0.092 9 0.107 9 0.163 10 0.554
 N1–2 36 28   26   25   23  
Differentiation
 High/moderate 40 30 0.208 27 0.485 24 0.446 22 0.119
 low/undifferentiated 14 8   8   10   11  
TNM
 I/II 22 11 0.007 9 0.002 10 0.027 11 0.165
 III/IV 32 27   26   24   22