ADAM-17 is a poor prognostic indicator for patients with hilar cholangiocarcinoma and is regulated by FoxM1

BMC Cancer

Table 1 Association between ADAM-10, ADAM-17, ADAM-28, and FoxM1 expression and clinical variables of hilar cholangiocarcinoma

Variables	N	ADAM-10	P	ADAM-17	P	ADAM-28	P	FoxM1	P
Gender
Male	38	27	0.866	23	0.309	22	0.235	20	0.049
Female	16	11		12		12		13
Size
≤ 3 cm	21	12	0.089	9	0.007	10	0.063	9	0.028
>3 cm	33	26		26		24		24
T stage
T1–3	7	2	0.009	3	0.192	3	0.238	3	0.288
T4	47	36		32		31		30
N stage
N0	18	10	0.092	9	0.107	9	0.163	10	0.554
N1–2	36	28		26		25		23
Differentiation
High/moderate	40	30	0.208	27	0.485	24	0.446	22	0.119
low/undifferentiated	14	8		8		10		11
TNM
I/II	22	11	0.007	9	0.002	10	0.027	11	0.165
III/IV	32	27		26		24		22

ISSN: 1471-2407