|
Primary tumor
|
Metastatic tumor
|
---|
PD-1
|
Median (range)
|
1.8 (0–8.4)
|
1.3 (0–11.2)
|
CTLA4
|
Median (range)
|
1.0 (0–5.4)
|
0.4 (0–2.0)
|
ICOS
|
Median (range)
|
3.0 (0–12.4)
|
2.6 (0.2–9.0)
|
GITR
|
Median (range)
|
0.9 (0–6.6)
|
0.4 (0–3.8)
|
HLA-DR
|
Median (range)
|
0.6 (0–3.0)
|
0.4 (0–2.2)
|
Granzyme B
|
Median (range)
|
1.2 (0.4–4.4)
|
1.0 (0–2.8)
|
The PD-1/CD8 ratio
|
Median (range)
|
0.32 (0–10.5)
|
0.41 (0–15.0)
|
The FOXP3/CD4 ratio
|
Median (range)
|
0.79 (0–11.5)
|
0.86 (0.2–12.5)
|
- PD-1 Programmed cell death 1, CTLA4 cytotoxic T-lymphocyte-associated protein 4, ICOS inducible T-cell co-stimulator, GITR Glucocorticoid induced tumor necrosis factor receptor related protein, HLA-DR Human Leukocyte Antigen - antigen D Related, FOXP3 Forkhead boxprotein P3