Table 2 LAST Study Measurement of Patient-Reported Outcomes

PROMIS Fatigue^a

PROMIS Depression^a

PROMIS Sleep Disturbance^a

PROMIS GI Symptoms - Diarrhea^a

PROMIS GI Symptoms - Nausea

PROMIS Physical Function

PROMIS Anxiety

PROMIS Sleep Related Impairment

PROMIS Pain Interference

PROMIS Pain Intensity

PROMIS Ability to Participate in Social Roles and Activities

PROMIS Social Isolation

PROMIS Applied Cognition General

PROMIS Interest in Sexual Activity

PROMIS Satisfaction with Sex Life

PROMIS Alcohol Use

PROMIS Global Self-Rated Health

PROMIS Global Quality of Life

EORTC CML Symptom Burden (includes 1 item on musculoskeletal pain^a)

Ability to work

Ability to pay monthly bills

Changes in use of pharmaceuticals