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Table 5 Associations of stress-related mental disorders around cancer diagnosis with hospital admission, a stratification analysisa

From: Mental disorders around cancer diagnosis and increased hospital admission rate - a nationwide cohort study of Swedish cancer patients

 

Main discharge diagnosis of hospital admission

 

Any hospital admission; HR (95% CI)b

External injury; HR (95% CI)

Infection; HR (95% CI)

Cardiovascular disease; HR (95% CI)

Sex

 Male

1.42 (1.32–1.52)

2.12 (1.76–2.55)

1.35 (1.05–1.72)

1.25 (1.06–1.47)

 Female

1.28 (1.20–1.37)

1.68 (1.43–1.97)

1.24 (0.98–1.57)

1.05 (0.89–1.23)

Age at follow-up, years

  ≤ 65

1.36 (1.27–1.45)

1.99 (1.56–2.53)

1.44 (1.11–1.87)

1.20 (0.96–1.51)

 66–75

1.36 (1.25–1.49)

1.85 (1.47–2.34)

0.98 (0.72–1.35)

1.19 (0.94–1.52)

  > 75

1.21 (1.11–1.31)

1.62 (1.36–1.94)

1.25 (0.92–1.70)

1.01 (0.86–1.19)

Calendar period at diagnosis

 2004–2006

1.34 (1.25–1.44)

1.84 (1.57–2.17)

1.15 (0.91–1.45)

1.11 (0.96–1.30)

 2007–2009

1.36 (1.28–1.45)

1.93 (1.61–2.31)

1.42 (1.11–1.83)

1.25 (1.03–1.52)

Educational level

  > 9 years

1.34 (1.26–1.43)

1.96 (1.66–2.32)

1.29 (1.04–1.59)

1.09 (0.93–1.29)

  ≤ 9 years

1.36 (1.27–1.46)

1.75 (1.47–2.08)

1.28 (0.96–1.69)

1.20 (1.01–1.43)

Previous mental disorders

 No

1.32 (1.24–1.41)

1.86 (1.55–2.22)

1.40 (1.11–1.76)

1.01 (0.86–1.19)

 Yes

1.34 (1.25–1.43)

1.82 (1.53–2.15)

1.12 (0.87–1.43)

1.28 (1.06–1.53)

Cancer stagec

 Localized

1.48 (1.37–1.60)

2.01 (1.67–2.42)

1.15 (0.86–1.55)

1.21 (1.01–1.45)

 Local spread

1.27 (1.12–1.43)

1.92 (1.46–2.52)

1.44 (0.95–2.17)

1.36 (1.02–1.82)

 Regional spread

1.23 (1.12–1.37)

1.48 (1.06–2.06)

1.03 (0.67–1.61)

1.35 (1.01–1.79)

 Advanced

1.08 (0.95–1.22)

1.52 (0.94–2.45)

1.52 (0.80–2.87)

0.78 (0.51–1.21)

 Unknown

1.42 (1.27–1.60)

2.07 (1.56–2.73)

0.99 (0.65–1.50)

0.97 (0.73–1.29)

  1. aStress-related mental disorders included depression, anxiety, stress reaction and adjustment disorder, mental and behavioral disorders due to psychoactive substance use, and somatoform/conversion disorder
  2. bHR Hazard ratio, CI Confidence interval; models adjusted for age at cancer diagnosis, sex, calendar period of cancer diagnosis, cancer type, cancer stage at diagnosis, educational level, and history of mental disorders more than 90 days before cancer diagnosis; patients without any mental disorders from 90 days before to 90 days after cancer diagnosis were used as the reference group
  3. cPatients with missing or unclear information of TNM/FIGO were classified as ‘Unknown’