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Fig. 5 | BMC Cancer

Fig. 5

From: The kallikrein-Kinin system modulates the progression of colorectal liver metastases in a mouse model

Fig. 5

The effect of kinin receptor antagonists on MoCR and SW480 cell proliferation. a MoCR cells and b SW480 cells were cultured for 48 h in RPMI media in the presence of 0.10 μM of kinins (BK or DABK) and 10.0 μM of the B2R antagonist FR173657 (FR) or the B1R antagonist SSR240612 (SSR) in specific combinations. The control was RPMI media with no FBS, SSR240612 and FR173657 treatment significantly reduced tumor cell proliferation compared to control cells. Results are presented as replicate mean ± SD, 4 replicate per group (*p < 0.001; **p < 0.0001 compared with untreated control)

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BMC Cancer

ISSN: 1471-2407

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