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Table 6 Genes of up and down regulation (5-fold) after CEA stimulation in M0 macrophage

From: Carcinoembryonic antigen as a marker of radioresistance in colorectal cancer: a potential role of macrophages

Symbol

p-value (M0 + CEA vs. M0)

Log fold (M0 + CEA vs. M0)

Fold-Change (M0 + CEA vs. M0)

MMP12

0.0257923

0.701613

5.03052

FCGR1A

0.0422142

−0.70421

−5.06069

PNCK

0.0398482

−0.70525

−5.07281

PGA5

0.0297503

−0.7423

−5.52462

HGC6.3

0.0373702

−0.78718

−6.12611

GDF15

0.00840181

0.785626

6.10416

JAG1

0.0437505

0.720147

5.24985

SPINK1

0.00346519

1.14264

13.888

LOC645464a

0.0130519

0.739874

5.49381

  1. MMP12 = Matrix metalloproteinase-12
  2. FCGR1A = High affinity immunoglobulin gamma Fc receptor I
  3. PNCK = Pregnancy Up-Regulated Nonubiquitous CaM Kinase
  4. PGA5 = pepsinogen 5
  5. HGC6.3 = Human hypothetical LOC100128124
  6. GDF15 = Growth/differentiation factor 15
  7. JAG1 = Jagged1
  8. SPINK1 = serine protease inhibitor Kazal-type 1
  9. aThis record has been withdrawn by NCBI because the model on which it was based was not predicted in a later annotation