Table 3 Univariate and multivariate analysis of distant metastasis (DM)
Parameters | 5-year DM | p value | Hazard ratio (95% CI) | p value |
|---|---|---|---|---|
Age | Â | 0.459 | Â | 0.694 |
  < 57 | 53.2% |  | reference |  |
 ≥ 57 | 46.2% |  | — |  |
Stage | Â | 0.065 | Â | 0.100 |
 II | 35.5% |  | reference |  |
 III | 52.8% |  | — |  |
T stage | Â | 0.200 | Â | 0.286 |
 T2 | 0% |  | reference |  |
 T3 | 44.6% |  | — |  |
 T4 | 59.3% |  | — |  |
N stage | Â | 0.086 | Â | 0.149 |
 0 | 35.5% |  | reference |  |
 1 | 49.0% |  | — |  |
 2 | 62.0% |  | — |  |
APR | Â | 0.643 | Â | 0.667 |
 No | 47.3% |  | reference |  |
 Yes | 53.7% |  | — |  |
Anal verge (cm) | Â | 0.071 | Â | 0.066 |
 ≤5 | 53.3% |  | reference |  |
 6–10 | 33.0% |  | — |  |
  > 10 | 84.1% |  | — |  |
Pretreatment CEA level | Â | 0.024 | Â | 0.026 |
  < 10 ng/mL | 40.6% |  | reference |  |
 ≥ 10 ng/mL | 73.1% |  | 1.923 (1.080–3.423) |  |