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Fig. 7 | BMC Cancer

Fig. 7

From: Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Fig. 7

Efficacy of 5-FU on cell migration and invasion in 4 T1 cells was enhanced by D5D-KD (via shRNA) and DGLA treatment. a Transwell migration assay of D5D-KD 4 T1 cells upon treatment of DGLA (100 μM), 5-FU (50 μM) alone or 5-FU + DGLA. The D5D-KD cells without fatty acid and drug treatment were used as controls; b Transwell invasion assay of D5D-KD 4 T1 cells upon treatment of DGLA (100 μM), 5-FU (50 μM) alone or 5-FU + DGLA. The D5D-KD cells without fatty acid and drug treatment were used as controls; and c Quantification of transwell migration and invasion assay of D5D-KD 4 T1 cells. Data represent as mean ± standard deviation (*: significant difference with p < 0.05 from n ≥ 3)

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BMC Cancer

ISSN: 1471-2407

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