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Table 4 Univariate Cox regression model of histotypes on disease specific survival

From: Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers

Histotype All cases Advanced stage Poor prognosis Low stage
Hazard 95.0% CI n   Hazard 95.0% CI n   Hazard 95.0% CI n   Hazard 95.0% CI   
Ratio Lower Upper   p value Ratio Lower Upper   p value Ratio Lower Upper   p value Ratio Lower Upper n p value
HGSC     1216 reference     940 reference     621 reference     206 reference
EC 0.19 0.14 0.26 274 0.000 0.51 0.34 0.77 49 0.001 0.85 0.48 1.51 18 0.575 0.20 0.12 0.34 214 0.000
LGSC 0.62 0.47 0.81 101 0.001 0.67 0.50 0.91 73 0.009 0.72 0.50 1.03 49 0.069 0.68 0.31 1.48 20 0.332
CCC 0.51 0.41 0.62 255 0.000 1.63 1.24 2.16 65 0.001 1.54 1.00 2.36 27 0.050 0.62 0.43 0.89 178 0.01
MC 0.35 0.23 0.53 86 0.000 2.95 1.58 5.52 11 0.001 13.82 6.41 29.79 7 0.000 0.48 0.26 0.88 72 0.017
  1. Bold values highlights the adjusted statistically significant difference with the reference category
  2. EOC epithelial ovarian cancer, n number of patients with follow-up, CI confidence interval, low stage: patients with stage I and II, advanced stage: patients with stage III and IV, HGSC High-Grade Serous Carcinoma, EC Endometrioid Carcinoma, LGSC Low-Grade Serous Carcinoma