Table 1 Clinical characteristics of patients
Variable | Category | Entire cohort (n = 861) | |||||
|---|---|---|---|---|---|---|---|
Adolescent and young adult patients n = 66 | Adult patients n = 795 | p value | |||||
Treatment Year | 1999–2004 | 25 (38%) | 251 (32%) | 0.291 | |||
2005–2013 | 41 (62%) | 544 (68%) | |||||
Gender | Male | 31 (47%) | 458 (58%) | 0.094 | |||
Female | 35 (53%) | 337 (42%) | |||||
ECOG performance status | PS 0, PS1 | 56 (93%) | 702 (94%) | 0.841 | |||
PS2, PS3, PS4 | 4 (7%) | 45 (6%) | |||||
missing data | 6 | 48 | |||||
Symptoms | Asymptomatic | 9 (14%) | 207 (26%) | 0.026 | |||
Symptomatic | 56 (86%) | 588 (74%) | |||||
Tumor location | Proximal colon | 21 (32%) | 227 (29%) | ||||
Distal colon | 26 (39%) | 359 (45%) | 0.663 | ||||
Rectum | 19 (29%) | 209 (26%) | |||||
M category | M1a | 34 (52%) | 404 (51%) | ||||
M1b | 14 (21%) | 196 (25%) | 0.784 | ||||
M1c | 18 (27%) | 195 (24%) | |||||
Tumor differentiation | Differentiated | 57 (86%) | 692 (87%) | ||||
Poorly differentiated | 6 (9%) | 76 (10%) | 0.217 | ||||
Mucinous | 1 (2%) | 20 (2%) | |||||
Others | 2 (3%) | 7 (1%) | |||||
Preoperative CEA levels | < 30 ng/ml | 35 (53%) | 399 (50%) | 0.672 | |||
≥30 ng/ml | 31 (47%) | 394 (50%) | |||||
Primary tumor resection | Yes | Curative resection | 13 (20%) | 34 (52%) | 210 (26%) | 508 (64%) | 0.029 |
Metastasectomy (−) | 21 (32%) | 298 (37%) | |||||
No | chemotherapy | 30 (45%) | 32 (48%) | 265 (33%) | 287 (36%) | ||
BSC | 2 (3%) | 22 (3%) | |||||