Pretreatment neutrophil to lymphocyte ratio in determining the prognosis of head and neck cancer: a meta-analysis

BMC Cancer

Table 2 Summary of meta-analysis results

Outcomes	Variable	N	References	Fixed-effect model		Random-reffect model		Heterogeneity
Outcomes	Variable	N	References	HR(95%CI)	p	HR(95%CI)	p	I2	p
OS	Ethnicity
	Asian	8	[24, 26, 29, 30, 34, 35, 37, 42]	1.72 (1.46,2.03)	< 0.001	1.87 (1.46,2.40)	< 0.001	49%	0.056
	Caucasian	6	[25, 33, 36, 38, 39, 41]	1.85 (1.44,2.37)	< 0.001	1.83 (1.34,2.51)	< 0.001	26%	0.239
	cutoff value
	2.1 < cutoff< 3	8	[24, 26, 29, 30, 34, 37, 38, 41]	1.63 (1.39,1.91)	< 0.001	1.71 (1.43,2.17)	< 0.001	47.60%	0.064
	3 < =cutoff< 4	3	[25, 35, 42]	1.88 (1.28,2.77)	0.001	1.95 (1.24,3.06)	0.04	18.30%	0.249
	cutoff> = 4	3	[33, 36, 39]	2.41 (1.70,3.44)	< 0.001	2.41 (1.70,3.44)	< 0.001	0	0.675
DFS		4	[25, 30, 34, 40]	1.99 (1.46,2.71)	< 0.001	1.99 (1.46,2.71)	< 0.001	0	0.457
MFS		3	[27, 28, 39]	1.92 (1.36,2.72)	< 0.001	1.92 (1.36,2.72)	< 0.001	0	0.614
PFS		5	[24, 29, 35, 38, 42]	1.60 (1.37,1.87)	< 0.001	2.17 (1.20,3.92)	0.01	91.30%	0

ISSN: 1471-2407