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Table 1 Characteristics and quality assessment results for each included publications

From: Pretreatment neutrophil to lymphocyte ratio in determining the prognosis of head and neck cancer: a meta-analysis

Study Country Ethnicity Tumors Patients(female/male) Age(range) Result Follow-up (month) Uni\Multi Cutoff value NOS Score
Sun et al, 2016 [24] China Asian NC 251 (71\180) 46 (15-76) OS PFS 50 (5-84) Multi 2.6 8
Wong et al, 2015 [25] UK Caucasian LSCC 140 (19\121) 66 (36-92) OS DFS 41 (2-103) Multi 3.1 8
Fu et al, 2016 [26] China Asian LSCC 420 (7\413) 60 (33-84) OS CSS ungiven Multi 2.59 7
An et al, 2011 [27] China Asian NC 363 (89\274) 47 (12-76) DSS MFS 62 (2-92) Multi 3.73 7
Li et al, 2015 [28] China Asian NC 363 (89\274) 47 (12-76) DSS 14.7 (3.22-92.9) Multi 2.81 8
He et al, 2012 [29] China Asian NC 1410 (383\1027) 46.1 (13-79) OS PFS 41 (2-60) Multi 2.74 7
Fang et al, 2013 [30] China Asian OCSCC 226 (19\207) 52.47 (27.0-84.0) OS DFS ungiven Uni 2.44 6
Nakahira et al, 2016 [31] Japan Asian NS 100 (14\86) 65.2 (37-85) CSS 37.85 (4-92) Multi 3 8
Perisanidis et al, 2013 [32] Austria Caucasian OCSCC 97 (30\67) ungiven DSS > 5 years or until death Multi 1.9 7
Charles et al, 2016 [33] Australia Caucasian HNSCC 145 (30\115) 63 (23-86) OS RFS 29 (1.5-84) Multi 5 8
Tu et al, 2015 [34] China Asian LSCC 141 (4\137) 59 (36-87) OS DFS 51 (5-102) Multi 2.17 7
Moon et al, 2016 [35] Korea Asian HNSCC 153 (24\129) 57 (16-78) OS PFS CSS 39.5 (4.7-62.6) Multi 3.3 8
Rachidi et al, 2016 [36] America Caucasian HNSCC 543 (123\420) 58.8 OS 64.4 (2-156) Multi 4.39 8
Song et al, 2015 [37] China Asian HSCC 146 (10\136) 57.5 (34-89) OS 33.2 (2-128) Uni 2.3 7
Salim et al, 2015 [38] Turkey Caucasian HNSCC 79 (8\71) 59 (28-85) OS ungiven Uni 2.93 6
Haddad et al, 2015 [39] Australia Caucasian HNC 46 (8\38) 59 (43-81) OS MFS RFS 34 (13-47) Uni 5 5
Rassouli et al, 2015 [40] Canada Caucasian HNSCC 273 (75\198) 64 + _12 DFS 45 (42-48) Uni 4.27 6
Selzer et al, 2015 [41] Austria Caucasian HNC 318 (121\247) ungiven OS ungiven Uni 1.58 7
Kim et al, 2016 [42] Korea Asian HNC 104 (9\95) 58 (20-82) OS PFS 39 (4.8-82.5) Multi 3 8
  1. NC nasopharyngeal carcinoma, LSCC laryngeal squamous cell carcinoma, OCSCC Oral Cavity Squamous Cell Carcinoma, HNSCC Head and neck squamous cell carcinoma, HSCC hypopharyngeal squamous cell carcinoma, HNC head and neck cancer, Uni univariate analysis, MFS metastasis-free survival, Multi multivariate analysis, NOS score Newcastle-Ottawa Scale score, > 5 meant relative good quality