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Fig. 7 | BMC Cancer

Fig. 7

From: Bexarotene inhibits the viability of non-small cell lung cancer cells via slc10a2/PPARγ/PTEN/mTOR signaling pathway

Fig. 7

Slc10a2 via PPARγ plays an important role in tumor suppressor with the treatment of bexarotene. a The expression of apoptotic related genes Bcl-2, cyclin D1, c-FLIP, caspase 3, caspase 7 in A549 cells and slc10a2 overexpressed A549 cells when treated with bexarotene, bexarotene in combination with GW9662 respectively; b The expression of tumor suppressor genes PTEN, P21, P53, LKB1, TSC2 in A549 cells and slc10a2 overexpressed A549 cells when treated with bexarotene, bexarotene in combination with GW9662 respectively. A549 cells without any treatment as control group. All experiments were repeated 3 times

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BMC Cancer

ISSN: 1471-2407

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