From: Cost effectiveness analysis of afatinib versus pemetrexed-cisplatin for first-line treatment of locally advanced or metastatic EGFR mutation positive non-small-cell lung cancer from the Singapore healthcare payer’s perspective
Afatinib arm
Pemetrexed-cisplatin arm
Median overall survival, months (95% CI)
28.2 (24.6–33.6)b
28.2 (20.7–33.2)b
Median first-line progression free survival, monthsa
11.1c
6.7c