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Table 4 Univariate analyses of the association of HLTF expression with overall survival and disease-free survival

From: Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC)

Outcome Overall survival (OS) Disease-free survival (DFS)
Category n Estimate at 5 years Logrank p-value HR (95% CI)a Wald
p-value
Estimate at 5 years Logrank p-value HR
(95% CI)a
Wald
p-value
WT <=20.6 86 61% 0.63 1.03 (0.97–1.1) 0.34 48% 0.14 1.01 (0.95–1.08) 0.72
> 20.6 85 64% 61%
I21R <=2.23 83 63% 0.65 1.03 (0.92–1.15) 0.61 58% 0.73 1.02 (0.93–1.13) 0.64
> 2.23 88 61% 49%
Composite covariable Wt > 20.6 or Mut < =2.23 146 65% 0.47 1.26 (0.67–2.34) 0.48 59% 0.0096 1.96 (1.17–3.3) 0.011
Wt < =20.6 and Mut > 2.23 25 50% 25%
  1. Cox proportional hazard regression model and log-rank test were used. A cut-off of p ≤ 0.05 was used for statistical significance
  2. aNote: HRs for WT HLTF represent the increase of the hazard for 10 units increase in the WT HLTF