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Table 3 Association of the composite covariate combining WT HLTF and I21R HLTF expression levels (n, %) with patient clinical characteristics

From: Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC)

Clinical factor Categories n WT < =20.6
Mut < =2.23
WT < =20.6
Mut > 2.23
WT > 20.6
Mut < =2.23
WT > 20.6
Mut > 2.23
p-value
Age Age < 65 57 20 (32.8%) 8 (32%) 10 (45.5%) 19 (30.2%) 0.62
Age > =65 114 41 (67.2%) 17 (68%) 12 (54.5%) 44 (69.8%)  
Sex F 78 26 (42.6%) 13 (52%) 11 (50%) 28 (44.4%) 0.85
M 93 35 (57.4%) 12 (48%) 11 (50%) 35 (55.6%)  
Stage I 121 46 (75.4%) 17 (68%) 15 (68.2%) 43 (68.3%) 0.81
II 50 15 (24.6%) 8 (32%) 7 (31.8%) 20 (31.7%)  
Histology ADC 122 40 (65.6%) 16 (64%) 17 (77.3%) 49 (77.8%) 0.78
OTH 49 21 (34.4%) 9 (36%) 5 (22.7%) 14 (22.2%)  
ADC 122 20 (32.8%) 8 (32%) 10 (45.5%) 19 (30.2%) 0.35
SCC 42 41 (67.2%) 17 (68%) 12 (54.5%) 44 (69.8%)  
  1. ADC Adenocarcinoma, OTH Other histology types, SCC Squamous cell carcinoma. The Mann-Whitney test was used. A cut-off of p ≤ 0.05 was used for statistical significance