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Table 3 Association of the composite covariate combining WT HLTF and I21R HLTF expression levels (n, %) with patient clinical characteristics

From: Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC)

Clinical factor

Categories

n

WT < =20.6

Mut < =2.23

WT < =20.6

Mut > 2.23

WT > 20.6

Mut < =2.23

WT > 20.6

Mut > 2.23

p-value

Age

Age < 65

57

20 (32.8%)

8 (32%)

10 (45.5%)

19 (30.2%)

0.62

Age > =65

114

41 (67.2%)

17 (68%)

12 (54.5%)

44 (69.8%)

 

Sex

F

78

26 (42.6%)

13 (52%)

11 (50%)

28 (44.4%)

0.85

M

93

35 (57.4%)

12 (48%)

11 (50%)

35 (55.6%)

 

Stage

I

121

46 (75.4%)

17 (68%)

15 (68.2%)

43 (68.3%)

0.81

II

50

15 (24.6%)

8 (32%)

7 (31.8%)

20 (31.7%)

 

Histology

ADC

122

40 (65.6%)

16 (64%)

17 (77.3%)

49 (77.8%)

0.78

OTH

49

21 (34.4%)

9 (36%)

5 (22.7%)

14 (22.2%)

 

ADC

122

20 (32.8%)

8 (32%)

10 (45.5%)

19 (30.2%)

0.35

SCC

42

41 (67.2%)

17 (68%)

12 (54.5%)

44 (69.8%)

 
  1. ADC Adenocarcinoma, OTH Other histology types, SCC Squamous cell carcinoma. The Mann-Whitney test was used. A cut-off of p ≤ 0.05 was used for statistical significance