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Table 3 Scoring system for the prediction of sorafenib response by using six covariates selected in the multivariable binary logistic regression analysis

From: Novel biomarker-based model for the prediction of sorafenib response and overall survival in advanced hepatocellular carcinoma: a prospective cohort study

Variable

Cutoff value

Score

bFGF (pg/mL)

< 2.0

0

2–5.5

1

≥5.5

2

Log PIVKA-II (mAU/mL)

< 30

0

30–1780

1

≥1780

2

BCLC stage

A, B

0

C

1

Etiology

Nonviral

0

HCV

1

HBV

2

Log HGF (pg/mL)

< 1380

0

1380–1860

1

≥1860

2

Platelet (×103/μL)

< 70

0

70–184

1

≥184

2

  1. Abbreviations: bFGF basic fibroblast growth factor, PIVKA-II protein induced by vitamin K absence-II, BCLC Barcelona Clinic Liver Cancer, HGF hepatocyte growth factor