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Table 3 Scoring system for the prediction of sorafenib response by using six covariates selected in the multivariable binary logistic regression analysis

From: Novel biomarker-based model for the prediction of sorafenib response and overall survival in advanced hepatocellular carcinoma: a prospective cohort study

Variable Cutoff value Score
bFGF (pg/mL) < 2.0 0
2–5.5 1
≥5.5 2
Log PIVKA-II (mAU/mL) < 30 0
30–1780 1
≥1780 2
BCLC stage A, B 0
C 1
Etiology Nonviral 0
HCV 1
HBV 2
Log HGF (pg/mL) < 1380 0
1380–1860 1
≥1860 2
Platelet (×103/μL) < 70 0
70–184 1
≥184 2
  1. Abbreviations: bFGF basic fibroblast growth factor, PIVKA-II protein induced by vitamin K absence-II, BCLC Barcelona Clinic Liver Cancer, HGF hepatocyte growth factor