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Table 3 Comparison of demographics of patients receiving different treatments stratified by nomogram points in the propensity model

From: Using nomogram of the Barcelona Clinic Liver Cancer system for treatment selection in patients with stage C hepatocellular carcinoma

Nomogram points/Absolute difference in propensity score of matched pairs

3–4.2 (n = 30)/< 0.0001

 

6.7–10 (n = 174)/0.0007

 

11.9–13 (n = 224)/0.0007

 

15.2–18 (n = 90)/< 0.0001

 

SR/Ablation/ TACE/ Transplant (n = 15)

Targeted/ Supportive (n = 15)

P/Stddiff

SR/Ablation/ TACE/ Transplant (n = 87)

Targeted/ Supportive (n = 87)

P/Stddiff

SR/Ablation/ TACE/ Transplant (n = 112)

Targeted/ Supportive (n = 112)

P/Stddiff

SR/Ablation/ TACE/ Transplant (n = 45)

Targeted/ Supportive (n = 45)

P/Stddiff

Age

75 ± 13

72 ± 10

0.92/0.14

63 ± 14

65 ± 14

0.21/0.18

63 ± 15

64 ± 14

0.06/0.3

59 ± 14

61 ± 13

0.094/0.16

Male (%)

13 (87)

14 (93)

1/0.14

65 (75)

66 (76)

0.86/0.18

84 (75)

93 (83)

0.14/0.3

35 (78)

39 (87)

0.27/0.61

HBV (%)

6 (40)

4 (27)

0.7/0.29

47 (54)

48 (55)

0.88/0.02

64 (57)

65 (58)

0.89/0.02

30 (67)

21 (47)

0.056/0.41

HCV (%)

5 (33)

7 (47)

0.46/0.27

27 (31)

22 (25)

0.4/0.13

19 (17)

23 (21)

0.49/0.09

9 (20)

13 (29)

0.327/0.21

Alcoholism (%)

2 (13)

2 (13)

1/0

10 (11)

13 (15)

0.5/0.1

28 (25)

32 (29)

0.55/0.08

11 (24)

14 (31)

0.48/0.15

CTP class A (%)

15 (100)

14 (93)

1/0.38

72 (83)

74 (85)

0.68/0.06

85 (76)

80 (81)

0.45/0.1

0

0

N/A

Ascites (%)

2 (13)

2 (13)

1/0

15 (17)

18 (21)

0.56/0.09

37 (33)

41 (37)

0.58/0.08

29 (64)

34 (76)

0.25/0.24

eGFR > 60 (ml/min/1.73m2)

5 (33)

5 (33)

1/0

62 (71)

65 (75)

0.61/0.08

83 (74)

79 (71)

0.55/0.08

37 (82)

33 (73)

0.311/0.22

Tumor > 5 cm

6 (40)

6 (40)

1/0

66 (76)

65 (75)

0.86/0.03

96 (86)

99 (88)

0.55/0.08

34 (76)

34 (76)

1/0

Single tumor (%)

11 (73)

8 (53)

0.26/0.42

56 (64)

47 (54)

0.17/0.21

57 (51)

50 (45)

0.35/0.13

23 (51)

21 (47)

0.673/0.09

Tumor burden 0/1/2/3

7/53/40/0

13/40/47/0

0.67/0.31

2/13/28/57

3/9/29/59

0.87/0.13

0/0/24/76

0/0/29/71

0.45/0.13

0/0/0/100

0/0/0/100

N/A

Performance status 0/1/2 (%)

40/40/20

47/33/20

0.9/0.15

60/22/18

62/23/15

0.83/0.09

0/71/29

0/71/29

1/0

29/47/24

20/40/40

0.266/0.35

Vascular invasion (%)

0

0

N/A

47 (54)

49 (56)

0.76/0.05

72 (64)

71 (63)

0.89/0.02

37 (82)

37 (82)

1/0

Metastasis/lymph node (%)

0

0

N/A

8 (9)

9 (10)

0.8/0.04

26 (23)

31 (28)

0.44/0.1

13 (29)

21 (47)

0.08/0.37

AFP > 400 ng/mL

3 (20)

3 (20)

1/0

44 (51)

42 (48)

0.76/0.05

65 (58)

61 (54)

0.59/0.07

22 (49)

28 (62)

0.203/0.27

Diabetes mellitus (%)

7 (47)

6 (40)

0.71/0.13

18 (21)

20 (23)

0.71/0.06

32 (29)

39 (35)

0.31/0.13

9 (20)

9 (20)

1/0

  1. SR surgical resection, TACE transarterial chemoembolization, Stddiff standardized difference, CTP Child-Turcotte-Pugh, eGFR estimated glomerular filtration rate, HBV hepatitis B virus, HCV hepatitis C virus