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Table 3 Cox regression analysis for eary RFS in 205 patients with resectable HCC

From: The clinical implications of G1-G6 transcriptomic signature and 5-gene score in Korean patients with hepatocellular carcinoma

  Univariate analysis Multivariable analysis
   95.0% CI    95.0% CI
P-value HR Lower Upper P-value HR Lower Upper
5-gene score (poor vs. good group) 0.023 2.087 1.106 3.936 0.361 1.373 0.696 2.708
Age (> = 60 vs. <  60) 0.469 1.113 0.833 1.488     
HBV 0.814 1.079 0.572 2.035     
HCV 0.044 1.476 1.010 2.156     
NBNC 0.100 0.772 0.567 1.051     
Tumor Nodules 0.000 5.308 2.474 11.390 0.000 5.956 2.554 13.892
Cirrhosis (Yes vs. No) 0.223 1.418 0.809 2.485     
VI (Yes vs. No) 0.009 2.131 1.21 3.754 0.904 0.959 0.483 1.901
Tumor size (> = 5 cm vs < 5 cm) 0.012 2.053 1.169 3.604 0.058 1.885 0.978 3.634
Edmonson Grade 0.985 0.997 0.74 1.344     
AFP level (Normal (< 20) vs. elevated) 0.001 3.192 1.631 6.248 0.004 2.823 1.387 5.745
RB1 mutation 0.009 2.62 1.27 5.413 0.488 1.318 0.604 2.873
TP53 mutation 0.769 1.094 0.602 1.987     
CTNNB1 mutation 0.338 0.702 0.341 1.447     
  1. *VI Microvascular Invasion