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Table 3 Cox regression analysis for eary RFS in 205 patients with resectable HCC

From: The clinical implications of G1-G6 transcriptomic signature and 5-gene score in Korean patients with hepatocellular carcinoma

 

Univariate analysis

Multivariable analysis

  

95.0% CI

  

95.0% CI

P-value

HR

Lower

Upper

P-value

HR

Lower

Upper

5-gene score (poor vs. good group)

0.023

2.087

1.106

3.936

0.361

1.373

0.696

2.708

Age (> = 60 vs. <  60)

0.469

1.113

0.833

1.488

    

HBV

0.814

1.079

0.572

2.035

    

HCV

0.044

1.476

1.010

2.156

    

NBNC

0.100

0.772

0.567

1.051

    

Tumor Nodules

0.000

5.308

2.474

11.390

0.000

5.956

2.554

13.892

Cirrhosis (Yes vs. No)

0.223

1.418

0.809

2.485

    

VI (Yes vs. No)

0.009

2.131

1.21

3.754

0.904

0.959

0.483

1.901

Tumor size (> = 5 cm vs < 5 cm)

0.012

2.053

1.169

3.604

0.058

1.885

0.978

3.634

Edmonson Grade

0.985

0.997

0.74

1.344

    

AFP level (Normal (< 20) vs. elevated)

0.001

3.192

1.631

6.248

0.004

2.823

1.387

5.745

RB1 mutation

0.009

2.62

1.27

5.413

0.488

1.318

0.604

2.873

TP53 mutation

0.769

1.094

0.602

1.987

    

CTNNB1 mutation

0.338

0.702

0.341

1.447

    
  1. *VI Microvascular Invasion
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