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Table 2 Expression analysis of Smurf2, CNKSR2, ER, PR and HER2 in non-malignant and malignant breast tissue samples

From: Regulation of CNKSR2 protein stability by the HECT E3 ubiquitin ligase Smurf2, and its role in breast cancer progression

  Grade of Tumour
Proteins studied Staining intensity Non-Malignant (n = 22) Malignant (n = 62) Total (n = 84) P-Value
Smurf2 No/Mild 16(72.73%) 6(9.68%) 22(26.19%) P < 0.001
Moderate/Intense 6(27.27%) 56(90.32%) 62(73.81%)  
CNKSR2 No/Mild 17(77.27%) 8(12.90%) 25(29.76%) P < 0.001
Moderate/Intense 5(22.73%) 54(87.10%) 59(70.24%)  
ER No/Mild 16(72.73%) 44(70.97%) 60(71.43%) P = 0.875
Moderate/Intense 6(27.27%) 18(29.03%) 24(28.57%)  
PR No/Mild 10(45.45%) 45(72.58%) 55(65.48%) P < 0.05
Moderate/Intense 12(54.55%) 17(27.42%) 29(34.52%)  
HER2 No/Mild 16(72.73%) 27(43.55%) 43(51.19%) P < 0.05
Moderate/Intense 6(27.27%) 35(56.45%) 41(48.81%)