Table 5 Multivariable Cox-proportional hazards analysis of predictors of 10- year disease-free survival
HR (95% CI) | p-value | |
|---|---|---|
Stage | ||
Regional | 2.9 (2.6–3.3) | < 0.001 |
Metastatic | 6.8 (5.9–7.9) | < 0.001 |
Tumor size | ||
≥ 2 to < 3 cm | 1.1 (0.9–1.2) | 0.297 |
≥ 3 to < 5 cm | 1.1 (1.0–1.2) | 0.156 |
≥ 5 cm | 1.8 (1.5–2.1) | < 0.001 |
Unknown | 1.1 (0.9–1.3) | 0.526 |
Radioactive iodine | ||
Yes | 0.7 (0.7–0.8) | < 0.001 |
Hospital volume (vs. average < 15 thyroidectomies yearly) | ||
15 to < 30 | 1.1 (0.9–1.2) | 0.242 |
30–55 | 0.8 (0.7–0.9) | 0.005 |
55+ | 1.0 (0.9–1.2) | 0.806 |
Surgery performed (vs. thyroid lobectomy) | ||
Completion thyroidectomy | 0.9 (0.6–1.2) | 0.419 |
Total thyroidectomy | 1.3 (1.1–1.6) | < 0.001 |
Total thyroidectomy with cervical lymphadenectomy | 1.6 (1.4–1.9) | < 0.001 |
Race (vs. non-hispanic white) | ||
Non-Hispanic Black | 1.0 (0.7–1.3) | 0.999 |
Hispanic | 1.3 (1.2–1.5) | < 0.001 |
Asian/Pacific Islander | 1.2 (1.1–1.4) | 0.003 |
Other race/Unknown | 1.0 (0.8–1.3) | 0.887 |
Age | ||
45–59 | 1.2 (1.1–1.4) | 0.001 |
≥ 60 | 1.9 (1.7–2.2) | < 0.001 |
Gender | ||
Female | 0.8 (0.7–0.9) | < 0.001 |
Comorbidities (vs. none) | ||
1 | 1.3 (1.1–1.5) | < 0.001 |
2 or more | 1.4 (1.0–1.8) | 0.026 |
Insurance (vs. private/hmo) | ||
Medicare | 1.1 (0.9–1.3) | 0.270 |
Medicaid/Indigent | 1.2 (1.0–1.4) | 0.016 |
County/Tricare/Military/VA | 1.9 (1.2–3.0) | 0.003 |
Not Insured/Other/Unknown | 3.3 (2.4–4.6) | < 0.001 |