Fig. 3
From: Integrated genomic analysis identifies clinically relevant subtypes of renal clear cell carcinoma
a Enrichment plot of upregulation pathways in EC1. GSEA of expression data from EC1 441 with worse prognosis, as compared to EC2–3. X-axis is the enrichment score of each gene. Y-axis represents the order of the gene in dataset. b Volcano plot of differential genes. Red color: up-regulated in EC1. blue color: down-regulated in EC1. Grey: not differential genes. Size of the bubble: mean expression of each gene C box plot of mean expression level on G1/S and G2/M gene set. EC1 is higher than EC2–3. c The heatmap of ccRCC expression data of GEO. The ccRCC expression profile of GEO has similar pattern with TCGA