Table 20 Characteristics of included studies- leukemia
From: Associations between aspirin use and the risk of cancers: a meta-analysis of observational studies
Study source | Sex | Study period | Source of subjects | No of case | No of control/cohort size | Cancer site | Exposure assessment | Exposure Definition | Adjustment for covariates | Study quality |
|---|---|---|---|---|---|---|---|---|---|---|
Case-control studies | ||||||||||
Ross JA [257], 2011, US | M/F | 2005–2009 | The MCSS | 734 | 697 | Leukemia | Questionnaire | Use at least once per week for at least 1 year | 1,7,10 | 9 |
Weiss JR [258], 2006, US | M/F | 1981–1998 | RPCI | 169 | 676 | Leukemia | Questionnaire | Use at least once per week for 6 months(regular) | 1,2 | 6 |
Oleske D [7], 1985, US | M/F | 1975–1981 | Hairy Cell Tumor Registry and Treatment Center | 45 | 134 | Leukemia | Questionnaire | Use three times a week or more for more than 2 months | 1,2,6,11 | 6 |
Cohort studies | ||||||||||
Jacobs EJ [98], 2007, US | M/F | 1992–2003 | Cancer Prevention Study II Nutrition Cohort | 465 | 146,113 | Leukemia | Questionnaire | Use at least 30 “times” per month(daily use of adult-strength) | 1,2,3,5,10,11,12,13,14,15,16,17,18,19 | 8 |
Kasum CM [259], 2003, US | F | 1992–2000 | IWHS | 81 | 28,224 | Leukemia | Questionnaire | Had ever taken aspirin- not further defined | 1,3,5 | 8 |
Friis S [62], 2003, Denmarka | M/F | 1989–1997 | Population from North Jutland County | 69 | 29,470 | Leukemia | Prescription database | 75–150 mg once daily(low-dose aspirin) | 1,2 | 8 |
Schreinemachers DM [63], 1994, US | M/F | 1971–1987 | The National Health and Examination Survey Ι | 39 | 12,668 | Leukemia | Self reported | Use aspirin during the 30-day period before the interview | 1,2 | 6 |