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Table 2 Characteristics of ovarian cancer patients visiting HCP for BRCA1 or BRCA2 testing in British Columbia by serous status, 2001–2013

From: A population-based analysis of germline BRCA1 and BRCA2 testing among ovarian cancer patients in an era of histotype-specific approaches to ovarian cancer prevention

  Serous ovarian cancer N = 581 Endometrioid or clear cell ovarian cancers N = 134 p-value
Age at diagnosis 60.0 ± 11.1 51.3 ± 11.0 < 0.001
Year of diagnosis 2007.9 ± 4.3 2005.3 ± 5.2 < 0.001
Age at time of first visit to HCP 62.3 ± 11.4 55.1 ± 11.3 < 0.001
Year of first visit to HCP 2009.6 ± 3.4 2008.4 ± 3.3 < 0.001
Index test
 Index 564 (97.1) 129 (96.3)  
 Carrier 17 (2.9) 5 (3.7) 0.237
Proband status
 Yes 527 (90.7) 116 (86.6)  
 No 54 (9.3) 18 (13.4) 0.151
Number of first degree relative
 0–3 423 (72.8) 97 (72.4)  
 4–6 122 (21.0) 32 (23.9)  
 7+ 36 (6.2) 5 (3.7) 0.455
Number of second degree relatives
 0–3 257 (44.2) 58 (43.3)  
 4–6 189 (32.5) 53 (40.0)  
 7+ 135 (23.2) 23 (17.1) 0.180
Number of third degree relatives
 0–3 303 (52.2) 62 (46.3)  
 4–6 164 (28.2) 38 (28.4)  
 7+ 114 (19.6) 34 (25.4) 0.290
Number of fourth degree relatives
 0–3 545 (93.8) 122 (91.0)  
 4–6 14 (2.4) a < 5%  
 7+ 22 (3.8) a < 5% 0.323
BRCA1 or BRCA2 positive 124 (21.3) 10 (7.5) < 0.001
  1. aSuppressed due to small cell sizes so approximate percentages have been reported